National Center for Design of
Biomimetic Nanoconductors
Atul Parikh
Contact:
Atul Parikh is currently Associate Professor of Applied Science in the Department of Engineering at the University of California, Davis. His current research interests include membrane bioengineering, membrane biophysics, microporous and mesoporous silica materials and thin films, and general soft condensed matter.
Research
Parikh’s current research includes the development and use of membrane mimetic platforms for biological and chemical sensing platforms, fundamental studies of membrane-dynamics, and membrane-protein interactions as applied to cell surface signaling processes for atherosclerosis and apoptosis. His principal characterization expertise include quantitative applications of optical/photonic spectroscopy and microscopy tools including fluorescence imaging methods, optical microscopies, infrared spectroscpy, imaging and spectroscopic ellipsometry, and scanning probe microscopy. Other projects include fundamental investigations of dynamic self-assembly, developing optical alternatives to ion-channel based biosensing, and understanding the role of lipid microenvironments and rafts in interactions between lipoproteins and endothelial cells.
Within the Center, the Parikh group will collaborate directly with Prof. Jeff Brinker in designing microarrays of synthetic silica nanopores and the optical characterization of single molecule transport and with Prof. Hagan Bayley for incorporating alpha-hemolysin based engineered nanopores in membrane patterns. Their associations with theoretical groups will be coordinated by Prof. Eric Jakobsson with respect to theoretical predictions of transport properties and will interact with the Feller/Scott team on molecular simulations for understanding the interactions between membrane microenvironments and pore-channels.
Related Publications
M. Boiling, J. E. Lincoln, Y. Yeh, D. G. Gilchrist, A. N. Parikh, L. S. Morse, Fas signaling induces apoptotic raft formation in human RPE cells that is blocked by cholesterol depletion, J. Investigative Opthalmology & Visual Science (JIOVS), in press, 2006.
A. R. Sapuri-Butti, J. T. Groves, A. N. Parikh, Non-equilibrium patterns of Cholesterol-rich membrane Heterogeneities,Langmuir in press, 2006
A. M. Brozell, M. A. Muha, B. Sanii, A. N. Parikh, A New Class of Supported Membranes: Bilayers on Photonic Band-gap Colloidal Crystals, J. Amer. Chem. Soc, in press, 2006
A. M. Brozell, M. A. Muha, A. N. Parikh, Formation of Spatially-Patterned Colloidal Photonic Crystals Through a Control of Capillary Forces and Template Recognition, Langmuir, 21, 11588-11591, 2005
Q. Li, M. L. Amweg, C. K. Yee, A. Navrotsky, A. N. Parikh, Photochemical Template Removal and Spatial Patterning of Zeolite MFI Thin Films Using UV/Ozone Treatment, Micropor. Mesopor. Mat. 87 45–51, 2005.
M. C. Howland, M. S. Johal, A. N. Parikh, Transition from Homogeneous Langmuir-Blodgett Monolayers to Striped Bilayers Driven by a Wetting Instability in Octadecylsiloxane Monolayers, Langmuir 21, 10468-10474, 2005.
A. A. Levchenko, C. K. Yee, E. Moloy, A. N. Parikh, A. Navrotsky, Energetics of Self-assembly and Chain Confinement in Silver Alkanethiolates: The Enthalpy-Entropy Interplay, Chem. Mater. 17, 5428-5438, 2005
Doshi DA, Dattelbaum AM, Watkins EB, Brinker CJ, Swanson BI, Shreve AP, Parikh AN, Majewski J, Neutron reflectivity study of lipid membranes assembled on ordered nanocomposite and nanoporous silica thin films, Langmuir 21 (7): 2865-2870, 2005.
A. Sharma, M. Dokhanian, A. Sileshi, A. N. Parikh, Interferrometrically Induced 190 nm grating formation in azo-dye-labeled phospholipid thin films using 244 nm light, Optics Lett 30 (5): 501-503, 2005.