C. Jeffrey Brinker holds appointments as Professor in the Departments of Chemistry and Chemical and Nuclear Engineering at the University of New Mexico, and as a Sandia Fellow in the Self-Assembly of Nanostructures Department at Sandia National Laboratories. His research interests include Silica sol-gel chemistry, inorganic polymers, controlled porosity materials, fundamentals of film formation, defects in glasses and gels, novel inorganic materials, sensors, inorganic membranes, nanostructured/nanoconfined composites, aerogels, self-assembled structures, nanocrystals, bio-nano interface, and superhydrophobicity.
Brinker has combined sol-gel processing with molecular self-assembly in a process called Evaporation-Induced Self-Assembly (EISA) that enables the efficient formation of porous and composite nanostructures from homogeneous sols through simple evaporative procedures. More recently, Brinker’s group has extended their original work on EISA in several significant ways including the direct writing of functional self-assembled nanostructures using computer-driven pens and ink-jet printers, the self-assembly of photosensitive films that incorporated molecular photoacid generators, and the synthesis of environmentally sensitive nanostructures.In the Center, nanoporous silica membranes prepared by EISA will be used as supports for lipid bilayers/transmembrane proteins that maintain fluid, water-rich biotic/abiotic interfaces, serve as reservoirs for ions, and provide long-term membrane bilayer stabilities. Based on their controlled pore size and pore surface chemistry, EISA-prepared membranes will also be developed as robust, totally synthetic ion channel-mimetic architectures that dispense completely with the need for lipid bilayers. Brinker’s group has developed novel techniques for synthesis, spatial patterning, and surface modification of inorganic nanostructures as well as lipid bilayers and ion channels – these capabilities will be combined to demonstrate a prototype power source based on natural bio-batteries. In addition to synthesis, quite importantly Brinker’s group has unique expertise in acquiring single channel recordings/stochastic signatures of natural and synthetic ion channels supported on solid substrates. Solid-supported ion channel architectures are essential for development of rugged miniaturized devices needed for implantable sensor systems, arrays, and power sources. Brinker’s work on embedding ion channels and other transporter in solid substrates will be key to engineering the components of the biobattery. His and Atul Parikh’s work on replicating the Bayley results in a different experimental environment will be key to assessing transferability of functional data from one environment to another.
Self-assembly and integration of ordered, robust, three-dimensional gold nanocrystal/silica arrays, Science, 304 (2004) 567-71.
Photoregulation of mass transport through a photoresponsive azobenzene-modified nanoporous membrane, Liu, N.G., Dunphy, D.R., Atanassov, P., Bunge, S.D., Chen, Z., Lopez, G.P., Boyle, T.J., Brinker, C.J., NanoLetters, 4 (2004) 551.
Evaporation-induced self-assembly: functional nanostructures made easy, Brinker, C.J., MRS Bulletin 29 (2004) 631.
Self-assembly of mesoscopically ordered chromatic polydiacetylene/silica nanocomposites, Lu, Y., Yang, Y., Lu, M., Huang, J., Fan, H., Haddad, R., Lopez, G., Burns, A.R., Sasaki, D.Y., Shelnutt, J., Brinker, C.J., Nature, 410 (2001) 913-917.
Optically-Defined Multi-Functional Patterning of Photosensitive Thin-Film Silica Mesophases, Doshi D., Huesing N.K., Lu M., Fan H., Simmons-Potter K., Potter Jr. B.G., Hurd A.J., Brinker C.J. Science, 290 (2000) 107-111.
Rapid prototyping of patterned functional nanostructures, Fan, H., Lu, Y., Stump, A., Reed, S.T., Baer, T., Schunk, R., Perez-Luna, V., Lopez, G.P., Brinker, C.J., Nature, 405 (2000) 56-60.
Evaporation-Induced Self-Assembly of Hybrid Bridged Silsesquioxane Film and Particulate Mesophases with Integral Organic Functionality, Lu, Y., Loy, D.A., Assink, R.A., Lavan, D.A., Doke, N., Fan, H., Brinker, C.J., J. Am. Chem. Soc., 122 (2000) 5258-5261.
Aerosol-Assisted Self-Assembly of Mesostructured Spherical Nanoparticles, Lu, Y., Fan, H., Stump, A., Ward, T.L., Reiker, T., Brinker, C.J., Nature, 398 (1999) 223-226.
Silica aerogel films at ambient pressure via surface derivatization and reversible drying shrinkage, Prakash, S.S., Brinker, C.J., Hurd, A.J., Rao, S.M., Nature, 374, (1995) 439-443.
Microporous Silica Prepared by Organic Templating: Relationship Between the Molecular Template and Pore Structure, Lu, Y., Cao, G., Kale, R.P., Prabakar, S., Lopez, G.P., Brinker, C.J., Chem. Materials, 11, (1999) 1223-1226.
Evaporation-Induced Self-Assembly: Nanostructures Made Easy, Brinker, C.J., Lu, Y., Sellinger, A., H. Fan, Adv. Mater., 11, 7, (1999) 579-585.
Continuous Formation of Supported Cubic and Hexagonal Mesoporous Films by Sol-Gel Dip-CoatingY. Lu, R. Ganguli, C. A. Drewien, M. T. Anderson, C. J. Brinker, W. Gong and Y. Guo, H. Soyez, B. Dunn, M. H. Huang, and J. I. Zink, Nature, 389 (1997) 364-368.